Label-free Optical Micro Imaging of Tissue Histology in vivo

Date: 11:00am, April 12, 2016
Location: Davis Auditorium
Speaker:  Xingde Li, Professor Department of Biomedical Engineering, John Hopkins University

Abstract: This seminar will focus on our recent progresses on developing high-resolution biophotonic imaging technologies, particularly the second-generation optical coherence tomography (OCT) endoscopy and multiphoton endomicroscopy. These technologies have shown significant translational potential for imaging tissue microanatomies in vivo at a resolution approaching or at standard histopa- thology but without the need for tissue removal, staining or processing. The physics principles, engineering challenges and solutions will be briefly dis- cussed, including the development of advanced lasers, MEMS technology, custom optical fiber, and ultracompact, high-performance imaging optics. Rep- resentative applications of these high-resolution technologies will be presented, including cancer detection, airway physiology imaging, preterm birth risk as- sessment, and intra-operative guidance for neurosurgery. Other potential appli- cations towards basic research such as functional neuroimaging on awake ani- mals will also be discussed.  
Biography:  Dr. Xingde Li received his PhD degree in Physics and Astronomy from the University of Pennsylvania in 1998. He is currently a professor at the Department of Biomedical Engineering, Johns Hopkins University. He has published more than 90 peer-reviewed journal papers, with a total citation ~11,100 and an H-index~44 (according to Google Scholar). In addition, several of his patents have been licensed. He has delivered more than 130 invited talks (including plenary talks) at conferences and outside research institutions. He served as the chair of Emerging Technologies Committee of IEEE-EMBS (2006-2010). He has chaired many conferences such as the recent OSA Biomedical Optics Topical Meetings 2010-2014. He serves on serval funding review panels including the NIH Biomedical Imaging Technologies (BMIT), NSF, Singapore and EU. He has been a topical editor or associate editor for several international journals including the Journal of Biomedical Optics (SPIE), Biomedical Optics Express (OSA), the IEEE Transactions on Biomedical Engineering, Light: Science and Applications (Nature Publishing Group and CIOMP) etc. He is a Fellow of OSA, SPIE, and AIMBE.
Hosted by Professor Christine Hendon

500 W. 120th St., Mudd 1310, New York, NY 10027    212-854-3105               
©2014 Columbia University